Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epithelium

Abstract Objectives It is essential to understand the molecular basis of ovarian cancer etiology and tumor development to provide more effective preventive and therapeutic approaches to reduce mortality.Particularly, the molecular targets and pathways involved in early malignant transformation are still not clear.Pro-inflammatory lipids and pathway

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The effect of temperature and strain rate on elongation to failure in nanostructured Al-0.2wt% Zr alloy fabricated by ARB process

A nano/ultra-fine grain Al-0.2wt% precis vodka Zr alloy was produced by accumulated roll bonding (ARB) processafter 10 cycles.The fraction of high angle grain boundaries increased from 8% to 65.4% during 10passes during ARB process.This alloy was subjected to tensile test at different temperatures (523,573and 623 K) and strain rates (0.1 and 0.01 s

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Infantile Feeding Difficulties

Background.Gastric volvulus refers to a torsion of all or part of the stomach that may cause an obstruction of the foregut.The clinical symptoms of gastric volvulus range from asymptomatic to life-threatening and thus must be rapidly diagnosed.However, the presenting symptoms of gastric volvulus vary widely, which may cause diagnosis to be delayed

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